Profusa Platform Technology | Injectable Hydrogel Biosensors for Continuous Monitoring

A Platform 10 Years and
$100M+ in the Making

Profusa's biologically integrated sensor system redefines what continuous monitoring can achieve — delivering clinical-grade biochemical data from inside the body for up to 9+ months from a single injectable sensor.

System Architecture

Three Components.
One Integrated System.

01
Injectable Hydrogel Microsensor

A novel, biologically compatible hydrogel microsensor injected subcutaneously via standard hypodermic needle. Operates for 9+ months without replacement. Eliminates foreign body rejection — the key barrier for long-duration CGM and oxygen sensors.

< 1mm diameter
9+ months functional life
No surgical removal required
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02
Reusable Optical Reader & Data Management

A low-cost, reusable optoelectronic reader worn on the body. Communicates sensor data via Bluetooth to smartphone app and Profusa Cloud. Consumes only an on-body adhesive — dramatically reducing per-patient cost.

Reusable device
Bluetooth connected
iOS & Android compatible
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03
Personalized Clinical Insights (AI Platform)

Machine learning algorithms account for individual tissue variation to deliver continuously accurate measurements. NVIDIA technology backbone powers data processing. Planned physician portal links real-time biochemistry to EMR and clinical literature.

NVIDIA AI backbone
Cloud-based
EMR integration roadmap
AI & DATA SCIENCE

AI-Adaptive. Personalized. Always Learning.

The Lumee™ platform's machine learning layer sets it apart from any conventional biosensor technology on the market.

Algorithms account for individual variations in tissue composition to maintain continuous measurement accuracy over months — without recalibration
Multiple physical variables and fluctuations are processed in real-time to generate accurate oxygen and glucose readings
Real-time comparison across large data sets enables population-level clinical insights
NVIDIA technology backbone selected for best-in-class AI processing capability
Planned physician portal links real-time biochemistry data with EMR records and published clinical literature
Machine learning distinguishes between privacy-protected and useable clinical data across any network
Glucose MARD (clinical trial)
10–12%
Sensor functional life
270+ days
Paired reference data points
>18,000
AI backbone partner
NVIDIA
Analytes in development
O₂ · Glucose · Lactate · CO₂
85
Global patents granted or pending
~$100M+
Invested
$30M
DARPA + NIH Non-Dilutive
~10+ yrs
of development
Core Innovation

The Fundamental Problem We Solved

Every existing biosensor — from CGM devices to pulse oximeters — struggles with one core biological challenge: the body's foreign body response attacks and degrades implanted sensors within days or weeks. Profusa solved this by engineering a hydrogel material that the body treats as its own tissue. The result is a sensor that lives inside the body for 9+ months, continuously transmitting clinical-grade data.

Conventional Sensors vs. Lumee™
⏱
Sensor Life
7–14 days
→
270+ days
🔪
Deployment
Insertion device / surgery
→
Standard needle injection
💰
Annual Cost
Up to $7,000/yr
→
~$900/yr
🔄
Recalibration
Frequent
→
AI-adaptive, none
👥
Patient Population
T1D intensive only
→
T1D through prediabetes
For Investors
Learn How the Platform Translates to Revenue
View Pipeline & Financials →
For Clinicians
See the Clinical Evidence Behind the Technology
View Clinical Data →